Sentence examples for bind to the nucleotide from inspiring English sources

Prior results showed that either ADP or ATP could bind to the nucleotide binding site of PII and that wild-type heterotrimers could sense the ratio of ATP to ADP, a reflection of the adenylate energy charge (10).

It was recently reported that VER155008 could bind to the nucleotide binding site of Hsp70 protein, and then could act as ATP-competitive inhibitor, which prevents allosteric control between nucleotide binding domain and substrate binding domain, although 2-phenylethynesulfonamide interacted with the substrate binding domain of Hsp70 in an unspecific and detergent-like fashion [ 32].

Taken together, these results indicate that exogenous plant miRNAs are able to enter the serum and organs of mammals via food intake, and that plant MIR168a can bind to the nucleotide sequence located in exon 4 of mammalian LDLRAP1, leading to the inhibition of LDLRAP1 expression in vivo.

The loss of ATP-hydrolysis activity, assumed to be caused by an inability to bind to the nucleotide, abolished the formation of holocytochrome c (lane 2 lower strip; wild-type levels are shown in lane 1).

Similarly, synthetic small molecules that bind to the nucleotide-binding pocket in Ire1 (Additional file 1, Figure S4) can be described by Pcof.

Furthermore, we found that ADP was also able to efficiently inhibit autophosphorylation of Ire1α, consistent with it being able to bind to the nucleotide-binding site in the unphosphorylated enzyme contrary to previous suggestions (see above).

In our efforts to abrogate DDX3 functions in vivo, we synthesized a small molecule inhibitor, RK-33, which was designed to bind to the nucleotide-binding site within the DDX3 protein and abrogate its functionality.

New nucleotides align with and bind to the nucleotides of the existing strands, thus forming two DNA molecules that are identical to the original DNA molecule.

Description: Structure of tellurium-centred Anderson-Evans polyoxotungstate (TEW) bound to the nucleotide binding domain of HSP70.

VER, which binds to the nucleotide binding site of HSP70, acts as an ATP-competitive inhibitor.

Structures of the closely related Staphylococcus aureus multidrug transporter (SAV1866) have been obtained with either ADP bound or the nonhydrolyzable AMP-PNP bound to the nucleotide binding sites.