Sentence examples for bind to the mitochondrial from inspiring English sources

Positron emission tomography (PET), using radioligands that bind to the mitochondrial 18 kDa translocator protein (TSPO), allows in vivo quantification of microglia in their activated state [2].

Hexokinase-II (HKII) is highly expressed in the heart and can bind to the mitochondrial outer membrane.

In the cell or in cell-free assays with cellular extracts, Bax can reversibly bind to the mitochondrial membranes without fully integrating or pore formation.

Consistent with its role in apoptosis, HS1 is able to bind to the mitochondrial protein HAX-1, a Bcl2 like protein [ 40].

Although the published cohort of patients with complex II deficiency is small, mutations which affect the ability of complex II to bind to the mitochondrial membrane are evolving to be the most deleterious.

Although the exact process of aminoglycoside induced deafness is unknown it is thought that the m.1555A > G mutation enables aminoglycosides to bind to the mitochondrial ribosomes more readily than the normal genetic sequence.

Oligomerized Bak may bind to the mitochondria, altering mitochondrial membrane potential (Fig.  4d) and causing a cytochrome c release (Fig.  4e).

This oxidation can be carried out by two forms of glycerol-3-dehydrogenase, one bound to the mitochondrial membrane, and one freely dispersed in the cytosol.

Some studies have presented a similar mechanism of action for the antileishmanial drug paromonycin, which binds to the mitochondrial 30S ribosomal subunit as well as the induction of respiratory dysfunction and depolarization of the mitochondrial membrane [82, 83]. Figure 6 summarizes these two hypothesized mechanisms of growth inhibition of leishmania using a pool of flavonoids in EEP or NRPE.

Hexokinase, involved in the first regulatory step, appears predominantly in an HK2 isoenzyme form in tumors that is bound to the mitochondrial outer membrane facing the cytosol.

Electrons from respiratory substrates competitively converge from the various dehydrogenases to the CIII-associated quinone pool and are then conveyed to cytochrome oxidase and molecular oxygen by cytochrome c loosely bound to the mitochondrial inner membrane.