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A recent study [50] has shown that the HP1α can also associate with other HP1 isoforms which in turn can bind to the linker histone H1b.
Linker histones of the H1 family bind to the linker DNA regions connecting adjacent nucleosomes in the chromatin fiber.
One primer is designed to bind to the linker, and the other binds to the retroviral sequence.
The latter bind to the linker regions connecting adjacent nucleosomes and further contribute to the folding of the chromatin fiber.
Since both chaperones bind to the linker histones, we reasoned that hNAP1 and SET might function as anti-repressors; enhancing transcription by opposing H1-induced repression.
Linker histones bind to the linker DNA regions at the entry and exit sites of the nucleosome resulting in a structure that protects the DNA from digestion by micrococcal nuclease by an additional 20 22 bp termed as chromatosome [ 8].
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Nucleosome core particles are linked by short stretches of DNA bound to the linker histones H1 and H5 to form a nucleosomal filament that is folded into higher-order structure of chromatin fiber.
MeCP2 induces chromatin condensation in three successive steps: first, it binds to the linker DNA between nucleosomes; second, it brings the nucleosomes together in a 'stem conformation' through DNA protein interactions, and third, it binds to the nucleosomes themselves to produce full chromatin compaction [60].
Potentially, the spacing between nucleosomes may be specified by which CAP is bound to the linker region (e.g. HMGD1 or H1).
16 This method relies on the nature of the particular functional group on the surface of the magnetic particles that binds to the linker molecule and involves several additional chemical steps.
When Ca2+ binds to the linker, the two fluorescent proteins are drawn closer together, and the FRET efficiency between them increases; measuring the ratio of donor and acceptor emission provides a metric for Ca2+ binding.
More suggestions(16)
bind to the surface
bind to the novel
bind to the duplex
bind to the peptide
bind to the promoter
bind to the estrogen
bind to the tyrosinase
bind to the target
bind to the arabinoxylan
bind to the basal
bind to the dialysis
bind to the host
bind to the cell
bind to the AhR
bind to the block
bind to the lipophilic
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