It must bind tightly to the invading virus.
To see if RIT could be useful against an invading pathogen, Kate Dadachova, a biologist at the Albert Einstein College of Medicine in New York City, and colleagues designed antibodies to bind to the surface of Cryptococcus neoformans, a tenacious fungus that plagues AIDS patients.
In this process, phagocytic receptors at the cell surface bind to an invading microorganism, inducing receptor clustering, which in turn initiates phagocytosis.
The bacteria bind to and invade M cells within the follicle-associated epithelium overlying the lymphoid follicles of the Peyer's patches (PPs) [13], [14].
In the future, these antibodies will recognize and bind to an invading virus and stop it from infecting cells.
Antibodies are proteins that bind to specific invading molecules or organisms and either inactivate them or signal their destruction.
Infection experiments of cultured cell lines with C. jejuni have shown that the bacteria can bind to (Bind+), invade into (Inv+) and survive inside a defined intracellular compartment (Surv+), called the Campylobacter-containing vacuole.
In this study, Chen et al. reveal the high-resolution structure of PfRh5, the protein from Plasmodium falciparum that forms a complex with other proteins to allow the parasite to bind to, and invade, red blood cells.
This news soon flashed to Corinth, Miss., a mere 20 miles to the south, where the renowned Confederate general Albert Sidney Johnston had gathered 45,000 rebel soldiers bound to the destruction of Yankee host invading Southern soil.
Following nuclear and cell division that occurs at the schizont stage, newly formed merozoites are released from the infected cell, and these merozoites bind to and invade new red blood cells.
