Sentence examples for bind to the human from inspiring English sources

We used phage display to identify peptides and synthetic antibodies that specifically bind to the human proapoptotic death receptor DR5.

These two complexes can bind to the human telomeric DNA and have shown different features on DNA stability, binding stoichiometry, and sequence-dependent fluorescence enhancement.

Here, we set out to develop a general strategy for the synthesis of bivalent compounds that are projected to bind to the human gonadotropin-releasing hormone receptor (GnRHR).

The finding, described in this week's Nature, may help neurobiologists screen for drugs that bind to the human version of this brain receptor.

Drugs that bind to the human Ether-a-go-go Related Gene (hERG) potassium channel and block its ion conduction can lead to Torsade de Pointes (TdP), a fatal ventricular arrhythmia.

Isothermal titration calorimetry (ITC) measurements confirmed that these self-assembling immunofibers can bind to the human immunoglobulin G class 1 (IgG1) with high specificity at pH 7.4, but with significantly weakened binding at pH 2.8.

The mode of interaction of this series with PPARγ was corroborated through the X-ray crystal structure of 12b bound to the human PPARγ ligand binding domain.

As shown in Figure 6B, DOSS binds to the human PPARγ ligand-binding domain with a KD of 1,380 nM.

In its crystal structure, (PDB code: 3GID), where Sarophen A is bound to the human ACC 2, the binding site residues are given as Lys274-Ser278-Arg277-Glu593-Met594-Asn599-Asn679-Trp681-Phe704-Trp706. functiona shofs total coresidueon, CT as a functindexf residue index and the residues between Phe704 Ser715, exhibit non-zero values of CT, obtained by using 3GLK.pdb.

Eculizumab is a recombinant humanized monoclonal IgG2/4k antibody that binds to the human C5 complement protein, inhibiting its cleavage to C5a and C5b and preventing the generation of the terminal complement complex C5b-9 [ 2, 3].

However, both TPP and ITP (which contains 40% TPP) bound to the human PPARγ LBD, interacted with binding hot spots within the LBD, activated PPARγ1 transcriptional activity, and stimulated adipogenesis.