Sentence examples for bind to the endogenous from inspiring English sources

Domain-swapping and chromatin immunoprecipitation studies have shown that selective HIF target gene activation is not based on the DNA-binding properties of these factors, since both HIF-α subunits can bind to the endogenous HREs of hypoxia-responsive genes, but that selectivity resides in their C-terminal regions, harboring their transcriptional activation domains.

To determine whether Nur77 can bind to the endogenous Cbl-b NurRE, we performed chromatin immunoprecipitation (ChIP) assay.

Furthermore, both receptors also bind to the endogenous 60 kDa HSP (HSP60), leading to cell activation [ 10, 11].

We found that both BRCA1 and ER α bind to the endogenous IGF-1 promoter region containing an estrogen-responsive element-like (EREL) site.

To determine whether the generated mAbs selected against ectopically expressed PFF0620c, PFD1130W or PF14_0325 would bind to the endogenous proteins of P. falciparum parasites, we performed IFA and Western-blot analysis using cultivated blood-stage parasites and mosquito salivary gland-derived sporozoites.

An ensemble of five cAMP-dependent protein kinase structures, all bound to the endogenous co-factor adenosine 5′-triphosphate (ATP) (Additional file), was retrieved from the PDB [1].

Rizatriptan benzoate (RB) is the second generation of triptans and 5-HT1D receptor agonist that binds to the endogenous serotonin (5-hydroxy tryptamine) (Visser et al. 1996).

Here, we report the crystal structure of a silkworm PIWI-clade Argonaute, Siwi, bound to the endogenous piRNA, at 2.4 Å resolution.

The efficacy of the chemotactic response is comparable to the stimulation with the chemokine CCL2 which binds to the endogenous CCR2.

Our results on mHS62 are in agreement with a previous study [14] and confirm that CTCF binds to the endogenous mouse HS62 fragment.

Monocytic THP-1 cells transfected with the α2A-adrenoceptor (α2AAR) display comparable signal transduction responses, such as calcium mobilization, MAP-kinase activation and chemotaxis, to the noradrenaline homlogue UK 14'304 as when stimulated with CCL2, which binds to the endogenous chemokine receptor CCR2.