Sentence examples for bind to the common from inspiring English sources

Hence, the effect of the decoction on their binding suggest that it may contain some compound(s), which either bind to the common antigenic moiety of these toxins or may directly block the GM1 on the cell membrane thereby inhibiting their binding to the receptor.

These proteins associate with receptor kinases and are phosphorylated at an SSXS motif of C-terminus, and then typically bind to the common mediator Smad4.

Members of the gp130 cytokine family, such as LIF or OSM, bind to the common signal transducing receptor chain gp130 and a second signalling receptor LIFR or OSMR [ 14].

The receptor-activated Smads 2 and 3 bind to the common smad 4, forming a complex that moves towards the nucleus, where it can modulate gene expression and promote activins biological effects [ 10].

In the canonical BMP pathway, the type I receptor phosphorylates receptor-regulated SMAD (homologue of Drosophila Mothers Against Decapentaplegic) proteins (R-SMADs, SMAD-1/5/8), which then bind to the common mediator SMAD4; the resulting SMAD complex translocates to the nucleus to regulate transcription of target genes [ 1].

The cytoplasmic domains of the EPOR contain a number of phosphotyrosines that are phosphorylated by the activation of a member of the Janus-type protein tyrosine kinase family (JAK2), which is bound to the common beta subunit of the EPOR [13].

This activates JAK2, which is bound to the common beta subunit of the EPOR [13] and leads to phosphorylation of tyrosine residues of the EPOR, which activates a number of signaling pathways (Figure 1).

Similarly, don't feel bound to the common pickling spices of mustard, peppercorns, dill and their brethren.

The chemical shift perturbation data reported here confirm that like other RPA32C interaction partners, SMARCAL1 binds to the common RPA32C interface.

This activates JAK2, which is bound to the common beta subunit of the EPOR [ 13] and leads to phosphorylation of tyrosine residues of the EPOR, which activates a number of signaling pathways.

One agent, ustekinumab (Stelara, Janssen Biotech Inc, Horsham, Pennsylvania, USA), is a human immunoglobulin G1 κ monoclonal antibody that binds to the common p40-subunit shared by IL-12 and IL-23.