Sentence examples for bind to the classical from inspiring English sources

CEPO: The administration of carbamylated EPO (CEPO), which does not bind to the classical EPOR, also provides renal tissue-protective effects.

For example, carbamylated EPO (CEPO) does not bind to the classical EPOR isoform and is devoid of hematopoietic activity; however, it can provide tissue protection in the kidney, supporting the existence of a heteroreceptor EPO isoform, which mediates tissue protection [27].

While Myc proteins have homology to other bHLHZ proteins and bind to the classical bHLHZ E-box CACGTG, they appear to be atypical members in a number of ways.

G1 is a specific GPR30 agonist that does not bind to the classical nuclear receptors [17] and that also activates the MAPK [44], [45] and PI3K signaling pathways [17].

However, results from several studies have revealed that BPA can stimulate rapid cellular responses at very low concentrations, below the levels where BPA is expected to bind to the classical nuclear ERs (Welshons et al. 2006).

For example, carbamylated EPO CEPOO) does not bind to the classical EPOR isoform and is devoid of hematopoietic activity; however, it can provide tissue protection in the kidney, supporting the existence of a heteroreceptor EPO isoform, which mediates tissue protection [ 27].

Human SP1 binds to the classical GC box three times stronger than the GA box (Letovsky and Dynan 1989; Wierstra 2008), and thus the ancestral preference for the GA box strongly suggests evolutionary changes in binding affinity.

Buprenorphine is a semisynthetic non-selective mixed opioid agonist antagonist and can bind to the three classical and the non-classical opioid receptors.

For example, all members of the vertebrate P120 family bind to the JMD of "classical" cadherins.

After digestion of the invariant chain by endosomal proteases, CLIP is dissociated from the groove by the non-classical class II DM molecule in the MIIC, and then other peptides, including those derived from exogenous antigens, can bind to the groove of the classical MHC class II molecule [ 1- 6].

LCM is a nonselective drug in terms of its sodium channel profile; however, it exerts 'selective' actions by enhancing only the slow inactivation of VGSCs, unlike other sodium channel blocking drugs that bind to the fast inactivation state (where classical antiepileptic drugs act) [ 44, 45].