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As an example, ELAV1/HuR, a potential mA-binding protein, was able to bind to the ARE region and stabilize corresponding transcripts [92].
Furthermore, this iAs-induced NRF2 protein was shown to bind to the ARE sequences in the promoter region of the K16 gene.
Overall, these findings clearly demonstrated that ligand-activated AR can bind to the ARE motif within the DAX-1 proximal promoter in human breast cancer cells.
In the present investigation, EMSA and supershift assays showed that the NRF2 proteins in the nuclei bind to the ARE sequences of K16 promoter region after iAs exposure.
Nrf2 can bind to the ARE (antioxidant-response element) [also called ERE (electrophile-response element)] sequence to activate transcription of antioxidant and cellular detoxification genes [ 112– 115].
Consistently, Nrf2 had the ability to bind to the ARE sites located within the promoter regions, as assessed by chromatin immunoprecipitation (ChIP) assays.
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Antibody bound to the wells was detected as described above.
Those expecting such thorough flash in "Dancer" are bound to be disappointed: the ride is somber, understated and chilling.
This was bound to be the case with the silver gilt cup that opened the session.
David Cameron, as the author of the referendum, was bound to be the de facto leader of Remain.
The pressure is bound to be on when you're the Champions League's youngest ever goalie.
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