Sentence examples for bind to the apical from inspiring English sources

They are composed of a cylinder-shaped protease lined on the interior with proteolytic sites and of ATPase rings that bind to the apical sides of the protease to control substrate entry.

It is thus likely that both factor H and FHL-1 bind to the apical epithelium.

The Hsp100 chaperones are also proposed to bind to the apical side of the peptidase, thus acting as entrance gates for unfolded polypeptides.

The proteins can be directly produced by the tumour cells and/or they can infiltrate from the blood to the ascites and then bind to the apical surfaces of tumour cells.

In the lower panels for the ILK-ko mice, it is evident that bacteria are able to bind to the apical region, however, there does not appear to be a comparable signal migrating downwards.

The structure of the SCARB2-JL2 complex revealed that JL2 binds to the apical region of SCARB2 involving α-helices 2, 5, and 14.

Purified HCP used at concentrations of 50, 100, and 200 µg/ml were incubated with cultured polarized HT-29 cell monolayers and after removal of unbound pili, HCP bound to the apical surface of the cells were detected by IFM (immunofluorescence microscopy) using anti-HCP antibodies (Fig. 3A).

Monoclonal antibodies to PECAM-1 will arrest leukocyte transmigration by 70 90% without interfering with normal leukocyte adhesion to endothelial monolayers; leukocytes remain tightly bound to the apical surface of the endothelial cell, precisely over the intercellular junction [ 56].

Binding of H3 HA-Fc to the tops of cilia was also markedly reduced after treatment with the α2-3 specific NA, but binding to the apical surface of cells lacking cilia persisted (Figure 5A, middle panel).

As well, the hyaluronan receptor CD44, expressed by many cancer cell types including ovarian and gastric cancer cells, enables these cells to bind to the hyaluronan-rich apical surface of mesothelial cells [ 31– 31].

Substrate protein binds more slowly than ATP and thus in vivo is likely to bind to the tilting and elevating apical domains.