Sentence examples for bind to the actin from inspiring English sources
Kindlin is known as an integrin binding and activating protein [ 94] that is also able to bind to the actin cytoskeleton via migfilin [ 1].
Both α-Syn and Tau are microtubule binding proteins; in addition, we have shown that α-Syn can also bind to the actin cytoskeleton [31].
While nectins bind to the actin cytoskeleton through afadin, CD155 does not [ 24], suggesting that CD155's cellular role is distinct from that of nectins.
To determine whether mDia1 and Daam1 bind to the actin cortex, we compared the half-time of fluorescence recovery after photobleaching of CA-mDia1 and Daam1 using actin as a positive control.
As α-catenin can bind to the actin filaments, the complex as a whole plays an important role of connecting E-cadherin thethe cytoskeleton, allowing it to regulate adhesion between cells [ 13, 14].
Nectins bind to the actin cytoskeleton through the adaptor protein afadin, the PDZ domain of which binds to a conserved amino acid motif (Glu/Ala-X-Tyr-Val) at the C-terminus that is present in all except nectin-4 and the truncated splice variants of nectins-1 and -3 (4, 5).
Active NPFs bind to the actin-related protein (Arp) 2/3 complex and promote its binding to the side of an existing actin filament, a reaction that allows the Arp2/3 complex to nucleate a new actin filament as a branch on the old filament (3, 4).
The proline-rich region binds to the actin binding protein, profilin, and the EVH2 domain is required for multimerization and direct F-actin binding in vitro [9].
This includes the ribosome-translocon complex of the endoplasmic reticulum which, after binding of the palmitoylated chaperone calnexin, binds to the actin cytoskeleton (Lakkaraju et al., 2012).
Tropomyosin bound to the actin filament will be locally constrained via binding interactions leading to poor excimer formation.
Studies have reported hypoxia-induced disorganization of the cytoskeletal network by disrupting F-actin filaments and by excessive cleavage of α-spectrin, an apical protein, that binds to the actin cytoskeleton and sodium transport proteins [42].
