Sentence examples for bind to target sequences from inspiring English sources

The antisense approach relies on AONs to efficiently bind to target sequences and depends on AON length, sequence content, secondary structure, thermodynamic properties, and target accessibility.

These then bind to target sequences to actively repress the transcription of target genes, or form non-DNA binding heterodimers with bHLH activators such as E47 and inhibit transcriptional activation [3].

Once the miRNA is in complex with Ago proteins, they bind to target sequences that are mainly located within the 3′ untranslated region (UTR) of a target mRNA.

miRNAs are short 18-222 noncodinges), noncoding RNAs that bind to target sequences in mRNA, typically resulting in post-transcriptional alteration of mRNA stability or translation efficiency.

The probes bound to target sequences are removed by a biotin streptavidin pull-down mechanism and the supernatant is analyzed by capillary electrophoresis.

The non-sex-specific OD1 is composed of an atypical zinc-finger domain (DM), which directly binds to target sequences on the DNA.

They are composed of 18 23 nucleotides and bind mostly to target sequences within the 3′ UTR or in rare cases to the coding region of their target mRNAs thereby inhibiting protein expression.

Upon stimulation with the cytokine interferon gamma (IFN-γ), STAT1 is trans-located to the nucleus to bind to target DNA sequences.

Zinc finger motifs are thought to recognize and bind to target DNA sequences, but they are not required for transcriptional activity [ 49, 50].

Zinc finger proteins are classified by the presence of zinc finger domains, which bind to target DNA sequences and regulate transcription.

The short CREI-96 (lacking one zinc finger) can still bind to target DNA sequences in vitro, which leads in vivo to a clear protection pattern from DNA methylation at CREI-binding sites (compare Figures  2 and 3).