Sentence examples for bind to target cells from inspiring English sources

Instead, engineered NPs bind to target cells and stimulate receptor-mediated endocytosis – a physiological process that provides entry for the RNA they carry without compromising cell viability (Fig. 2).

However, T. cruzi isolates that bind to target cells using gp35/50 (T. cruzi I Amazon region) appear to stimulate adenylate cyclase activity that seems to participate in Ca2+ release from acidocalcisomes [ 55, 56]).

To improve the targeting of the gene carrier for efficient cancer therapy, specific ligands which can bind to target cell-surface receptors, such as peptides, folate and antibodies, have been coupled to gene delivery vectors, which can trigger receptor-mediated endocytosis [22 24].

The radiolabelled TP-1 and TP-3 MoAbs had immunoreactive fractions of 70%and67%7%, respectively, and bound to target cells with binding constants of 8.5 X 10 8) M-1 and 4.0 X 10 9) M-1, respectively.

Figure 8 shows ACGNPs bound to target cells with high specificity, despite the occurrence of some nonspecific binding and nonbinding, neither of which could dramatically alter the color of the assay solution as a consequence of the negligible increase in absorption and scattering of ACGNPs.

Activating receptors recognize ligands expressed by tumor cells or stressed cells or, in the case of CD16, antibodies (Ab) of the IgG class bound to target cells.

Binding to target cells revealed an immunoreactivity of at least 60% and good retention of enzyme activity.

When the Fc γ receptor on immune effector cells detects the Fc portion of the antibody bound to target cells, immune effector cells are recruited to attack the target cells (Lazar et al, 2006).

Separating aptamer binding to target cells from FSNP binding to aptamer may allow a larger number of aptamers to bind to each target cell, amplifying the fluorescence signal.

These surface-bound ligands recognize and bind specifically to target cells.

Lentiviral vectors produced without a viral envelope protein lack the ability to bind and fuse to target cells and are not capable of gene transfer in HepG2 cells under our experimental conditions (Markusic and Seppen, unpublished results).