Sentence examples for bind to surface receptors from inspiring English sources

I-EGF was allowed to bind to surface receptors at 4°C for 2 h as described above.

These proteins bind to surface receptors like LRP5/6 and frizzled proteins on the surface of mesenchymal cells, leading to signaling through β-catenin, which translocates to the nucleus and activated genes involved in bone formation.

These glycation products, in addition to causing structural changes in long-lived proteins, increase vascular permeability, interfere with nitric oxide mediated vasodilation, oxidize LDL, and bind to surface receptors for AGEs on macrophages and endothelial cells to induce the secretion of cytokines, growth factors, and reactive oxygen species (5).

However, a common drawback of all methods is that they depend on EpCAM markers that are not 100% specific (antibodies can bind to surface receptors on blood cells) and the methods for distinguishing actual tumor cells from contaminants are not dependable [ 56].

Other types of viruses encode fusogenic proteins (like influenza hemagglutinin), which do not bind to surface receptors, but which liberate a fusion peptide in the acidic milieu of endosomes and thus initiate viral host cell fusion following endocytic uptake of viral particles.

With respect to modulation of the immune response, HMGB1 binds to surface receptors expressed on dendritic cells (DCs), leading to the maturation of DCs, antigen processing, and a subsequent protective effect.

Other angiogenesis inhibitors, eg, sorafenib and sunitinib, bind to surface endothelial cell receptors or to downstream signaling pathway proteins to block angiogenesis.

Activation of NF-κB occurs in response to diverse stimuli, such as endotoxin, which bind to cell-surface receptors that in turn activate the canonic and/or noncanonic signaling pathway.

Activated dimerized TGF- β proteins bind to cell-surface receptors type 1 and 2 (TGFBR1 and TGFBR2); transmembrane serine/threonine specific kinases that interact and phosphorylate intracellular molecules [ 21].

A signal transduction pathway (STP) is a network of intercellular information flow initiated when extracellular signaling molecules bind to cell-surface receptors.

In addition to its antifungal activity, fluconazole has been demonstrated to bind to neutrophil surface receptors and to upregulate intracellular signalling pathways, leading to enhanced oxygen free radical release and chemotaxis in vitro [ 12].