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VisualSonics, an ultrasound-imaging company based in Toronto, has been evaluating contrast agents made up of gold nanorods attached to antibodies that bind to specific targets found in cancer cells.
The commercial rumblings around IPS cells call to mind the mid-1970s excitement about monoclonal antibodies, when researchers hoped to vastly improve cancer treatment with disease-fighting antibodies that would bind to specific targets on cells.
If these compounds selectively bind to specific targets then they could potentially be used more broadly in H1N1 influenza prevention or treatment.
The design and development of radiolabelled compounds that can be administered intravenously, enter the brain via the blood stream and subsequently bind to specific targets in the CNS constitute the current major challenge in the field of radiopharmaceutical chemistry.
Even though drugs are designed to bind to specific targets to treat specific diseases, many of them exhibit multiple off-target interactions, which can lead to drug safety problems.
Recent advances in fluorescence super resolution microscopy and protein labeling chemistry make possible the visualization and tracking of individual transcription factors as they diffuse and bind to specific targets in the nucleus of living mammalian cells (Mazza et al., 2012; Gavrilov et al., 2013; Izeddin et al., 2014; Chen et al., 2014b).
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RNA aptamers are ribonucleic acids that bind to specific target molecules.
We have developed a computational method for predicting recognition helices for C2H2 zinc fingers that bind to specific target DNA sites.
Thus, the p3 end of the bifunctional bacteriophages would be able to bind to specific target antigen, while the AuNPs were assembled along the coat of virus for signal generation.
Therefore, it is reasonable to hypothesize that in cancer cells AP-2α may bind to specific target genes, silence transcription, and propagate DNA methylation in order to stably silence tumor suppressors and DNA repair genes.
In this context usually antibodies are used to bind to specific target proteins and thus wield biological influence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com