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These proteins bind to specific sites on DNA and (for example) turn on expression of specific genes.
The technique depends on natural agents called zinc finger proteins whose role is to bind to specific sites on the genome and control adjacent genes.
The trans-acting elements are related to a group of transcription factors that bind to specific sites within promoter and/or enhancer regions [53, 54].
These include ligands such as antibodies and small molecules that bind to specific sites associated with PCa growth; for example, the prostate-specific membrane antigen (PSMA).
EMSA of a sample of SOX9 interaction sites confirmed that SOX9 was able to bind to specific sites found in the hybridization peaks of our ChIP-on-chip experiment.
Although it is known that miRNAs usually bind to specific sites in the 3'UTR region of targeted mRNA transcripts, the accurate identification of all miRNA target genes has not been possible yet.
Similar(43)
In this study, a new small-molecule-based reagent was designed to recognize and bind to specific site in protein.
Pea3 transactivated the WT1 promoter in transient transfection assays and bound to specific sites within the WT1 promoter in vitro.
The Hin recombinase binds to specific sites on DNA and mediates a recombination event that results in DNA inversion.
Alprazolam, like other benzodiazepines, binds to specific sites on the GABAA gamma-amino-butyric acid receptor.
Alprazolam, like other benzodiazepines, binds to specific sites on the GABAAreceptor.
More suggestions(15)
bind to specific regions
bind to specific types
bind to specific cysteines
bind to multiple sites
bind to specific sequences
bind to similar sites
bind to specific ligands
bind to different sites
bind to specific proteins
bind to specific cargoes
bind to adjacent sites
bind to basic sites
bind to independent sites
bind to specific patches
bind to specific antibodies
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