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Transcription factors are proteins which bind to specific sequences of DNA, called binding sites, enabling and controlling the expression of genes.
The DNA binding domain of ERs allows the receptors to bind to specific sequences in the promoters of estrogen-regulated genes.
R2R3 MYB genes tend to display limited homology (aside from the highly conserved DNA binding region), and the code by which R2R3 MYB genes bind to specific sequences has not been well elucidated [ 45, 48].
The activity of genes is governed by transcription factors, which bind to specific sequences of DNA units that lie close to the gene.
Zinc-finger proteins (ZFPs) bind to specific sequences in ERVs23, recruit the adaptor protein TRIM28/KAP1, and the histone H3K9me3 methyltransferase SETDB1 to silence TEs13,24,25,26,27,28.
Pyrrolo[2, 1-c][1, 4]benzodiazepines (PBDs) are potent inhibitors of nucleic acid synthesis because of their ability to recognize and bind to specific sequences of DNA and form a labile covalent adduct.
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Transcriptional activators bind to specific sequence elements in genes and initiate the recruitment of the molecular machines needed to decondense chromatin and activate transcription.
First, TFs bind to specific sequence motifs [ 2] that favor a local DNA structure recognized by the TF's DNA-binding domain.
Puf family members are usually identified by the presence of eight tandem Puf repeats of ∼35 39 amino acids [8] and the repeat binds to specific sequences in the 3' untranslated region (UTR) of a target mRNA.
A transcription factor is defined as a regulatory protein that binds to specific sequences in DNA and affects transcription of specific genes.
One type of recombinase binds to specific sequences of DNA bases and uses an amino acid in the enzyme usually serine or tyrosine to break and rejoin the DNA strands.
More suggestions(17)
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bind to specific cysteines
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bind to hybrid sequences
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