Sentence examples for bind to specific mRNA from inspiring English sources

To interrupt that process, antisense RNA therapies inject cells with RNA strands that bind to specific mRNA snippets, effectively blocking them from being read by ribosomes.

Recent proteomic studies comparing the composition of two neuronal RNPs, one containing Staufen and the other Barentsz, have shown that neuronal RNA granules are highly heterogeneous and potentially bind to specific mRNAs (Fritzsche et al., 2013).

Devoid of its ISC, it binds to specific mRNA stem loop structures called IRE to regulate the expression of proteins involved in iron homeostasis.

Tis11 binds to specific mRNAs and signals their degradation in response to iron limitation [ 25]; its role in zinc deficiency is not yet determined.

For example, the product of the FMR1 gene, the fragile X mental retardation protein (FMRP), binds to specific mRNAs and represses their translation.

All these data suggest a general mechanism for the herpesviral mRNA export factors which bind to specific viral mRNAs and recruit these transcripts to the cellular mRNA export TAP/NXF1 pathway through interaction with one of its adaptors such as Aly/REF, UAP56 or the shuttling SR proteins.

miRNAs are direct negative regulators of gene expression that bind to specific sequences within a target mRNA [ 2, 3].

These data suggest that miR-1 and miR-133a directly bind to specific sites on 3′UTR of PNP mRNA.

ASO are chemically modified stretches of single stranded DNA designed to bind to a specific mRNA and selectively suppress its translation.

In animals, translational control of specific mRNAs frequently involves trans-acting factors that bind to specific recognition elements in the 3'UTR and target eIF4F assembly at the cap structure [ 18].

Although it is known that miRNAs usually bind to specific sites in the 3'UTR region of targeted mRNA transcripts, the accurate identification of all miRNA target genes has not been possible yet.