Sentence examples for bind to specific downstream from inspiring English sources

The active GTP-bound form of Rac proteins bind to specific downstream effectors and thereby participate in various cellular events.

The dynamic model assumes that the expression profile of a target gene results from the kinetic activity of one or more specific regulators, which bind to the downstream target gene's promoter site and initiate the transcription of that target gene to exert its effect on the inflammation network.

These proteins bind to specific nucleotide motifs16, 17.

These proteins bind to specific sites on DNA and (for example) turn on expression of specific genes.

These toxins and factors bind to specific human proteins.

Pharmaceutical researchers need increased computing power to design drug molecules that bind to specific cell receptors.

NGF and EGF act as ligands, which, when bound to specific receptors, activate signalling pathways that alter downstream transcription factors, which in turn modulate downstream gene expression [ 16, 19].

Activated p53 binds to specific DNA sequences in the regulatory regions of downstream genes, resulting in cellular events such as cell cycle arrest and apoptosis [ 1– 4].

Activated p53 protein binds to specific target DNA sequences and stimulates transcription of a variety of downstream target genes.

The heterodimer then binds to specific DNA elements, termed dioxin response elements (DREs), within the regulatory regions of targeted genes to modulate expression, resulting in downstream physiological responses [ 3].

Radioiodine bound to specific vector molecules is also widely used.