Sentence examples for bind to sites of from inspiring English sources

Condensins might also preferentially bind to sites of DNA crossings, consistent with their higher binding affinity for structured DNA substrates [ 63, 110].

PARP1 contains zinc-finger motifs that allow it to detect and bind to sites of single-stranded DNA damage.

MeCP2 is a member of the MBD family of proteins whose biological function is to bind to sites of methylation in the genome.

Many repair proteins bind to sites of DNA damage, resulting in subnuclear "foci," but SLX4 forms foci in human cells even without DNA damage.

Next, we evaluated the colocalization of CLEC12A with galectin 3 and galectin 8, which are both known to bind to sites of bacterial-induced intracellular membrane damage as well as sites of sterile membrane damage (Thurston et al., 2012).

Moreover, these MVs can bind to sites of vascular injury through the interaction of P-selectin, present in activated platelets, and its ligand PSGL-1 (P-selectin glycoprotein ligand 1) [ 80, 81].

PARP1 detects and binds to sites of single strand DNA damage via the DNA-binding domain.

CENP-A also binds to sites of DNA damage and appears to have a role in DNA repair [7].

They are incorporated into an RNA induced silencing complex (RISC) that binds to sites of variable complementarity in target messenger RNAs, triggering their degradation and/or repressing their translation [1].

This protein detects and binds to sites of ssDNA damage, and then synthesizes poly (ADP) ribose (pADPr, PAR) and transfers it to acceptor proteins.

Among chemical approaches, covalent DNA adducts generated by the platinating antitumor drug oxaliplatin can sequester nuclear HMGB1, since HMGB1 avidly binds to sites of distorted DNA.