The anti-human EpCAM antibody is a mouse IgG2 class molecule, and the Fc region, which helps increase plasma half-life through FcRn interactions, also binds to several types of immune cells[27] when injected intravenously (an important contradistinction to frozen sections where this interaction can be blocked).
4′-iodo-4′-deoxorubicin binds to several types of amyloid and introduces catabolism of amyloid deposits.
We have previously described that the L1Tc C-terminus encodes a protein, termed C2-L1Tc, whash has NAC activity and binds to several types of nucleic acids [ 22].
WGA binds to several types of mammalian cells including pancreatic duct epithelial cells [ 72], prostatic cancer cells [ 73], arterial macrophages and smooth muscle cells [ 74, 75], glomerular capillary walls, mesangial cells and tubules of human kidney [ 59].
Such a combined model could then cater for proteins that bind to several ligand types (with non-identical binding sites per ligand) and that are regulated by multiple allosteric activators or inhibitors.
In addition to several metabolites that were shared with StAR (e.g. lanosterol, squalene, PtCho, diacylglycerol and LysoPtCho), PCTP was shown to bind reproducibly to several types of lipids including sphinganine, sphingosine, behenic acid and linoleamide.
In contrast to other cell types gp120 has the potential to bind to several receptors on DC including CD4 and several types of C type lectin receptor, not just exclusively DC-SIGN.
K8/K18 bind to several apoptotic proteins and type I keratins are established caspase substrates (Oshima 2002; Green et al. 2005; Marceau et al. 2007).
A mi-RNA can bind to several smRNA.
Angiopeoitin-1 is known to bind to several integrins [44] [46].
