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Moreover, peptides selected for binding to certain receptors bind to several sites on the receptor and activation might occur through conformational changes rather than multimerization [54].
However, the binding pattern of CTCF at −31 is not defined by a single peak of enrichment in ChIP-chip - it is likely to bind to several sites over at least 2 kb interval centered at −31.
The helicase could bind to several sites and need the interaction of Gno1 or Pfa1 in order to trigger its activity at specific sites.
Interestingly, TFIIIC is also known to bind to several sites across the S. cerevisiae genome, called ETC loci, which are similarly independent of RNA polymerase III localization (Moqtaderi and Struhl, 2004).
Similar(56)
In the narrow selectivity filter of each pore, Cl− are bound to several sites through electrostatic interactions with helix dipoles and the partial charges of protein residues.
mel-LHR has been reported to bind to several hundred sites along the chromosome arms, predominantly in pericentric regions [ 14].
During an elongation cycle, a tRNA binds sequentially to several sites in the 70S ribosome.
A mi-RNA can bind to several smRNA.
Angiopeoitin-1 is known to bind to several integrins [44] [46].
ANA bind to several nuclear antigens.
Interestingly, Cry1 and Cry2 were bound to several more such sites than were the other circadian factors (Supplementary File 3).
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