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Our previous in vitro assays demonstrated that RIN can bind to sequences of C(C/T)(A/T 6(A/G G, and that the preferential binding sequence is 'CCA(A/T)(A/t)(A/T ATAG' [ 6].
The splicing reaction is also regulated by a large number of non-SR factors, such as hnRNPs (heterogeneous nuclear ribonucleoproteins) which mainly bind to sequences of splicing silencers and act as splicing repressors [12].
Increasing concentrations of Myc-5, but not of the mismatch PI polyamide, bound to the eIF4G1 promoter oligo (Fig. 2b, lanes 2 5), suggesting that Myc-5 can specifically bind to sequences of their target gene-promoters.
An important determinant of gene promoter selectivity of activated ERs in vertebrates is their ability to bind to sequences of DNA called estrogen response elements (EREs) within the promoter of target genes (Hall et al., 2001).
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Reports suggesting the presence of this protein bound to sequences of the insulator present in the gypsy retrotransposon [43] prompted us to examine the possibility of a role for Topo II in insulator function.
EBF1 persists as homodimers in solution and when it binds to sequences of promoters that loosely fit the consensus 5′-CCCNNGGG-3′ [ 37].
The complex of R-Smad and co-Smad bind to sequence elements within the promoter of target genes to positively or negatively regulate gene transcription.
In order to increase MAGE detection rate in RT-PCR assay, here, we designed multiple MAGEs recognizing primers (MMRPs) that can bind to the sequences of cDNA of MAGE-1, -2, -3, -4a, -4b, -5a, -5b and-6 (MAGE 1 6) together.
We further studied the ability of HNF4α to bind to promoter sequences of HNF1α, ApoC2, GK, PKLR, ALDOB, and INS2 by EMSA supershift assays.
In the nucleus, the proteins bind to DNA sequences of the target gene with the consensus CC AT 6GG sequence, also known as the CArG box [ 14].
Pyrrolo[2, 1-c][1, 4]benzodiazepines (PBDs) are potent inhibitors of nucleic acid synthesis because of their ability to recognize and bind to specific sequences of DNA and form a labile covalent adduct.
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