Sentence examples for bind to sequence elements from inspiring English sources

The complex of R-Smad and co-Smad bind to sequence elements within the promoter of target genes to positively or negatively regulate gene transcription.

Puf proteins are generally known to bind directly to sequence elements located within the 3' untranslated region (UTR) of their target mRNAs.

Such an SR protein binds both to sequence elements on the pre-mRNA and to other components of the spliceosome.

Through this domain, the different NF-κB members interact to form various homo- and hetero-dimers and bind to κB sequence elements present in the promoter or enhancer regions of target genes [ 4].

Transcriptional activators bind to specific sequence elements in genes and initiate the recruitment of the molecular machines needed to decondense chromatin and activate transcription.

The majority of TP53 alterations consists of missense mutations within the DNA-binding domain (DBD) that lead to the synthesis of p53 proteins that have lost the ability to bind to sequence-specific DNA recognition elements.

It is true that most peak-calling algorithms are designed with transcription factors in mind, and such factors usually bind to short sequence elements (on the order of 10 bp).

An important determinant of gene promoter selectivity of activated ERs in vertebrates is their ability to bind to sequences of DNA called estrogen response elements (EREs) within the promoter of target genes (Hall et al., 2001).

NFE2L2 is a redox regulated transcription factor prominently expressed in Müller cells and astrocytes in the retina [ 8, 83] and binds to specific sequence elements in the 5′UTR of target genes.

PPAR α binds to sequence-specific target elements as a heterodimer with the retinoid X receptor (RXR).

SRF binds to sequences known as serum response elements, and is a member of the MADS (MCM1, Agamous, Deficiens, and ARF) box superfamily of transcription factors that can stimulate cell proliferation and differentiation [23].