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This enables them to specifically bind to recipient cell receptors, providing the possibility to create exosomes that specifically target one desired cell type.
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Asc10 expression on the donor cell surface promotes binding to recipient cells.
For each approach, techniques for manipulating HAC in donor cells in order to deliver HAC to recipient cells are required.
Biochemical and functional studies revealed that gesicles incorporated proteins from producer cells and could deliver them to recipient cells.
We then investigated the ability of ESMVs to transfer GFP to recipient cells.
38 Secretory cell free miRNAs were shown to transfer inhibitory signals to recipient cells.
Recent data indicate some miRs may act intracellularly, carried by HDL particles to recipient cells [ 47].
Donor CD8+ T cells are activated when their T-cell receptor (TCR) binds to recipient peptides presented in the context of recipient class I major histocompatibility complex (MHC) molecules (see Box 1 for a glossary of immunological terms).
VirD2 also covalently binds to the 5′ end of the T-DNA and guides its transfer from the bacteria to the recipient cell [ 4].
Eex inhibits transfer of a plasmid to a recipient cell harbouring the same element [ 24], and thus it is equivalent to a conjugation recipient mutant.
In doing so, miRNAs are delivered to the recipient cell and then they alter cell functions.
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CEO of Professional Science Editing for Scientists @ prosciediting.com