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This enables them to specifically bind to recipient cell receptors, providing the possibility to create exosomes that specifically target one desired cell type.
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Donor CD8+ T cells are activated when their T-cell receptor (TCR) binds to recipient peptides presented in the context of recipient class I major histocompatibility complex (MHC) molecules (see Box 1 for a glossary of immunological terms).
DOI: http://dx.doi.org/10.7554/eLife.10032.001 Most neurons send their messages to recipient neurons by releasing a substance called a 'neurotransmitter' that binds to receptors on the target cell.
Two isolated antibodies from vaccine recipients, CH58 and CH59, bind to lysine 169 in gp120 V2 (Liao et al., 2013), a position implicated by sieve analysis in blocking sequence-matched HIV-1 strains.
With the kazoo being such a seminal instrument in the 21st Century music scene and an integral part of music history, this Electric Kazoo with portable amplifier is bound to delight any recipient.
Charity does not bind the recipient to the donor, but the other way round.
These contractual obligations actually bind only the parties that agree to them, but in practice they are often passed to downstream users in the form of conditions on reuse that the original recipient feels bound to impose.
Yet America's system involves judges sitting in a secret court who issue secret data-collection orders which bind the recipients to secrecy.
A valuable gift, however, binds the recipient to the giver forever, and also signals surplus.
A company memo that infuriates its recipients is bound to get wider distribution than the intended receiver list.
"If you give something, the recipient is honor bound to give something back," he said.
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