Sentence examples for bind to overlapping sites from inspiring English sources

These data indicated that ERG and ESE3 could bind to overlapping sites in the EZH2 and Nkx3.1 promoters and regulate their transcription in opposite directions.

This latter finding, however, is consistent with the recent report that pppssRNA and short OHdsRNA bind to overlapping sites of the RIG-I RD, and that short dsRNAs will activate IFNβ via RIG-I upon transfection if they contain 5' mono-phosphates that apparently stabilize the dsRNAs intracellularly [25].

First, the activator Vac7p and the inhibitor Atg18p bind to overlapping sites, close to the site of Fab1p.

GSH and GS-X bind to overlapping sites on Kef, which are located in a cytosolic regulatory domain.

The motifs binding Creb, Atf and Vbp1 are similar (Additional file 2) and these transcription factors have been shown to bind to overlapping sites [ 48].

Bioinformatics studies indicate that antagonistic factors often bind to overlapping sites [ 21] whereas synergetic factors are often positioned within a fixed distance [ 20], often close to the multiple of 10.2 bp, the DNA double-helix pitch value [ 21].

Binding of other proteins is also expected to affect detectability, negatively if the two proteins compete for binding to overlapping sites, or positively if the two proteins bind cooperatively.

In conclusion, SCL and these repressors bind to overlapping and distinct functional categories of activated and repressed target genes.

{IGF1-R and PGR}, {Erbb2, IGF1R} and {EGFR and PGR or IGF1R} bind to ESR1 at overlapping sites but Erbb2 and PGR bind to ESR1 at different sites.

Studies suggest that all three inhibitors (MAG, Nogo, and OMgp) bind overlapping sites in the LRR repeat domains [2], [28].

Given that all three inhibitors (MAG, Nogo, and OMgp) bind overlapping sites in the leucine rich repeat (LRR) domains of NgR [2], [3], molecules that generally interfere with the binding of all three inhibitors would have the best efficacy.