Sentence examples for bind to other targets from inspiring English sources

The MicF sRNA is also known to bind to other targets including the global transcription factor Lrp, where it indirectly activates genes in the Lrp regulon via antisense base-pairing with the translation initiation region of lrp mRNA [ 44].

LY294002 has also significantly decreased the basal expression of VEGF and SK1, which could not be noticed with wortmannin (LY294002 is known bind to other targets unrelated to the PI3K family [ 22]).

However, if compounds show inactive results in a particular bioassay, then they can still be toxic because they may bind to other target sites.

They will bind more to other targets and will decrease their expression levels.

Combinatorial methods are being used to engineer knottins that can bind to other clinically relevant targets in cancer, and inflammatory and cardiac disease.

Typically, mature miRNAs regulate gene expression through sequence-specific binding to the 3′ UTR of a target mRNA, but recent evidence indicates that miRNAs can also bind to other regions of a target mRNA [ 24, 25].

Moreover, it may be that even if this precaution is taken, the antibody may still non-specifically bind to other family members of the target.

Antibodies are Y-shaped proteins that can target and bind to other molecules.

However, CRISPR RNA is reported to bind to other genomic locations that differ from the intended target site by a few nucleotides, demonstrating significant off-target activity.

The GFP target was put at the end so that all of the GFPapt molecules that were combined with the random RNA library would have an opportunity to bind to the other targets; the loading solution for the first selection round contained 40 nmol of the random RNA library (∼5 copies of each sequence in the 5 × 10 library) and 6.4 fmol of GFPapt in 1 mL of binding buffer.

The inclusion of KTS between ZF3 and 4 significantly reduces the DNA-binding affinity of WT1 and the +KTS isoform binds to other DNA targets (10).