Sentence examples for bind to multiple sites from inspiring English sources

19 It can be used as a phasing tool and only a few binding sites are necessary, whereas mononuclear heavy atoms must bind to multiple sites to provide useful phases, especially for large proteins.

This difference in the rate of decline of the probability for the different substates could indicate that multiple protamine molecules, despite their large charge and size, would bind to multiple sites in the RyR vestibule that would have differential sensitivity to the electric field.

A miRNA can also bind to multiple sites of a single lincRNA.

AZD9773 is clearly shown to bind to multiple sites on hTNFα by virtue of the size of the complex in solution, as well as the presence of multiple epitopes as revealed by a combination of different approaches.

GABPα and ETS1 bind to multiple sites, in particular two high affinity sites (sites 1 and 3 shown on Fig. 1A) to regulate the position of the expression boundary and at least one of these high affinity sites is required for reporter gene expression.

We show that the PRH oligomer binds to multiple sites within the human Goosecoid promoter with high affinity and that the binding of PRH brings about DNA distortion.

The PRE profiles obtained with the paramagnetic centre at either end of the DNA oligonucleotides are similar (Figs. 3B and C), indicating that MA binds to multiple sites on the DNA in two orientations differing by 180° [13], [13].

NF-κB directly binds to multiple sites on the nos2 promoter region in LPS-treated J774 cells (Fig.  6b).

Mechanistically, NR2F6 directly binds to multiple sites within the Il17a promoter locus and suppresses the DNA accessibility of endogenous NFAT in resting or suboptimally stimulated Th17 cells.

In previous work, we established that Af9 binds to multiple sites of the α-ENaC promoter to target Dot1a-mediated hypermethylationlation for repression of basal α-ENaC transcription [ 6– 8].

In the second pattern, each protein bound strongly alone, and FruA appeared to be binding to multiple sites.