Sentence examples for bind to multiple isomers from inspiring English sources

In contrast to paclitaxel, ixabepilone can bind to multiple isomers of β-tubulin, including the βIII isoform [ 78].

Ixabepilone - an epothilone B analog that increases polymerization but that, unlike the taxanes, has the capacity to bind to multiple isomers of tubulin - has been evaluated in the setting of patients pretreated with anthracyclines, taxanes, and capecitabine as well as in first-line metastatic treatment of patients treated with adjuvant anthracyclines.

Most Wnt proteins can bind to multiple Frizzleds and vice versa, suggesting redundancy in vivo.

Neurotrophin proteins bind to multiple receptors (p75, TrkA-C) to modulate survival, functional and degenerative intracellular signaling and synaptic function.

Thus, saccharides with multi-cis-diols will bind to multiple PBA molecules.

Of these sequences, 62 contained nonamers predicted to bind to multiple HLA supertypes.

As targeting only requires partial complementarity, a single miRNA can bind multiple mRNA transcripts and each mRNA can be bound to multiple miRNAs.

Measurement of specific isomers (e.g., the biologically active 8-iso-PGF2α) with liquid chromatography/mass spectrometry is preferable to enzyme immunoassay, although multiple isomers can be representative of oxidative lipid damage, and the liquid chromatography/mass spectrometry method in a study of this size is cost prohibitive (Il'yasova et al. 2012; Smith et al. 2011).

Thus, Gli2 binds directly to multiple sites located up- and downstream of the Ascl1 gene.

Now, you know that if the same group is in attendance at multiple weddings you're bound to need multiple dresses.

Screening experiments have identified individual peptides that bind to all the different isomers, suggesting that the binding grooves in the different isomers have some common features [ 62].