Sentence examples for bind to multiple 3'UTRs from inspiring English sources

One major difference between miRNA and siRNA is that siRNA is specific to a particular target via perfect sequence match, while one miRNA can bind to multiple 3'UTRs of target mRNAs via 6 8 nucleotides root-sequence match and thus inhibits multiple target genes.

For example over 500 HLA class I and over 100 class II HLA binding sequences of supertype alleles were predicted, with many of the nonamer sequences predicted to bind to multiple (2 to 9) individual class I alleles.

Recently, a new group 2 influenza A antibody (AT10_002) has been developed, which binds to multiple H3 and H7 subtypes.

Unlike Asf1, monomeric CAF-1 binds to multiple H3/H4 dimers, which ultimately promotes the formation of (H3/H4 2 tetramers on DNA.

Panomics´ SH3 domain Arrays are designed to determine whether a protein of interest binds to multiple SH3 domains (Panomics).

Since essentially all HLA class II molecules tested were shown to bind to multiple promiscuous HIV-1 epitopes [32], it is expected that most individuals could develop broad T cell responses.

From the heat map, some proteins, such as the proto-oncogene tyrosine kinase ABL1, appeared to bind to multiple synbodies (Figure 5B).

The annotated SLiMDom dataset reveals that many globular domain classes bind to multiple ELM classes (156 ELM classes annotated to 85 globular domain functional classes).

This suggests that miR-181b, predicted to bind to multiple MREs within the 3′-UTR of E2F1, is able to indirectly influence E2F1-regulated genes as a secondary consequence of E2F1's own regulation by miR-181b.

Several groups have tested these overall ideas further via bioinformatics studies on collections of hub proteins, and these studies support the common use of disordered regions by hub proteins to bind to multiple partners [ 130- 134].

Here we present a detailed examination of two divergent examples: 1) p53, which uses different disordered regions to bind to different partners and which also has several individual disordered regions that each bind to multiple partners, and 2) 14-3-3, which is a structured protein that associates with many different intrinsically disordered partners.