Sentence examples for bind to ligands in from inspiring English sources

Additional design constraints also apply, such as the need for palladium ions to bind to ligands in a square-planar geometry — which implies the convergence of exactly four edges at each vertex.

Alpha-dystroglycan is an essential link between the extracellular matrix and the muscle fiber sarcolemma, and proper glycosylation is critical for its ability to bind to ligands in the extracellular matrix.

CD62L is intensely glycosylated and its ability to bind to ligands in vitro depends on its glycosylation [29].

ACE-536 binds to ligands in the transforming growth factor-β superfamily that regulate late-stage erythropoiesis, including the GDFs GDF11 [ 8, 9] and GDF8, and thus functions as a ligand trap to block the interaction of these ligands with activin receptors on developing normoblasts and consequently reduce Smad 2/3 signaling.

The proteolytic cascade of the complement system is initiated when pattern-recognition molecules (PRMs) bind to ligands, resulting in the activation of associated proteases.

The specific percentage of cells bound to ligand in each well was calculated as (FU from ligand-coated wells) – (FU from BSA-coated wells) × 100/total FU added to each well.

Integrins could initiate the activation of RRAS when bound to ligands, which in turn might increase the avidity and affinity of these integrins to ligands, and thereby cause further integrin engagement.

Free or bound to ligands, polyubiquitins are found in different arrangements of ubiquitin subunits.

When zinc levels rise, the metal binds to ligand residues in the AD1 and AD2 regions of the protein and this binding inhibits the ability of these domains to promote transcription [ 6- 10].

Nrps are known as multi-functional co-receptors that bind to different ligands in different cell types (Gu et al., 2003; Gitler et al., 2004; Pellet-Many et al., 2008).

Writing in Nature, Laverty et al.1 and Masiulis et al.2 report the 3D high-resolution structures of an isoform of the GABAA receptor bound to different ligands in physiologically relevant conformations.