Sentence examples for bind to its target from inspiring English sources
Possibilities include selective import to the CCC, or possibly selective degradation of RLSB in the PCC if it was unable to bind to its target rbcL mRNA.
As the antibody-binding extracellular domain is absent, trastuzumab is unable to bind to its target with resulting loss of its efficacy.
In line with this view, the crystal structure of TALE also suggests that thymine is necessary for its recognition and binding to DNA, although few reports showed TALE could still bind to its target sequence without the thymine [ 23].
Smith, Reichow et al. have used electron microscopy to reveal that the disordered region has two important roles: it determines how far away from the anchoring protein that the active region of the kinase can operate, and it influences how efficiently the kinase can bind to its target molecule in order to induce phosphorylation.
These results suggest that the conjugate can enter the nucleus, bind to its target site, presumably as a stacked dimer, and up-regulate the expression of topoIIα by blocking the binding of NF-Y.
Substitution of the identical Arginine (R204) in hup63 results in an autosomal dominant disorder characterized by ectrodactyly, ectodermal dysplasia, and orofacial clefts (EEC) [35], which is most likely due to a functional failure of hup63 to bind to its target DNA.
Solid-phase radiolabeling binding assays to test IG3 ability to bind to its targets.
In addition, because our structure-function predictions led us to hypothesize a DNA-binding role for the mutated Arg, we wished to know if the R1092W mutation disrupted the ability of Zfp335 to bind to its targets in vivo.
When it binds to its target, copT, it inhibits the translation of repA1 [11].
The complement system can be activated via the classical, alternative or lectin pathway, which is activated when Mannose-Binding Lectin (MBL) binds to its target molecule.
Like Sontheimer, Olson's lab uses a synthetic version of the chlorotoxin protein, but the added fluorescent molecule acts like a flashlight – turned on only when it binds to its target.
