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Mixing of mRL with mNL cells gave an intermediate result; that is, they formed both separate and chimeric aggregates, suggesting that R- and N-cadherin can interact with each other although each has a preference to bind to its own type.
If the NrdR1 box is mutated, NrdR cannot bind and therefore FNR is able to bind to its own recognition site, which could explain the higher expression levels found in NrdR1 box mutants (similar to those of the wild-type) compared to NrdR2 box mutants.
Hes-1 can also bind to its own promoter, and repress transcription.
Furthermore, OsWRKY13 can bind to its own promoter, as revealed by gel mobility shift assays [ 9, 22].
Nanog can bind to its own promoter and form autoregulatroy and feedforward circuitry, and Li may enhance such feedforward regulation.
As reported before, AG protein is able to bind to its own intron sequence for autoregulation [ 7].
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At HCD, HapR accumulates to a level sufficient to regulate its target genes, but because it also binds to its own promoter, it prevents additional hapR transcription, and thereby prevents excessive accumulation of HapR.
"It is too bound to its own sectarian roots, and it is too tied to forces in Iraq which do not yield themselves to compromise".
Arabidopsis AtGL3 expression is controlled by an autoregulatory feedback loop, such that it binds to its own promoter to negatively regulate its own gene expression [ 58].
GRP7 auto-regulates its abundance via a negative post-transcriptional feedback loop; it binds to its own pre-mRNA and influences splice site selection [ 9, 10].
This antagonistic conformation of H12 is different from that observed in the structure of the RXRα-oleic acid in the fully antagonist RARα/RXRα heterodimer, where H12 of RXRα in complex with oleic acid binds to its own cofactor binding site [12].
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