Sentence examples for bind to extracellular molecules from inspiring English sources

Cells interact with their environment via receptors that bind to extracellular molecules; these events are then translated into functions by biochemical signaling networks.

Integrin molecules such as CD11b and CD18 can also bind to extracellular matrix components such as fibronectin, fibrinogen, laminin, and collagen, and this binding aids in the movement of neutrophils through extracellular matrices [ 1, 3, 4].

Functionally glycosylated α-DG is not only recognized by IIH6C4 antibody but also binds to extracellular matrix molecules such as laminin.

Secreted Maspin could bind to extracellular matrix components.

Pro-VEGF-C binds to extracellular matrix via its C-terminal domain.

We discovered ten proteins bound to extracellular hsp90α.

Other isoforms bind to cells (type VI) and to various extracellular molecules (type XI).

The large extracellular domain of integrins bind to ECM molecules while the intracellular domain is linked to cytoskeleton through intracellular focal adhesions (FAs) as demonstrated in Fig. 2. FAs are supramolecular complexes formed by more than 150 different proteins, including kinases, scaffold, and adaptor proteins, as well as actin linking proteins.

The ErbB signalling pathway is actually composed of several transmembrane receptors able to trigger several signalling pathways when they bind to an extracellular growth factor molecule.

Currently, two classes of EGFR inhibitors namely monoclonal antibodies (mAbs) and small molecules, which bind to the extracellular ligand-binding domain and the intracellular tyrosine kinase domain of the EGFR, respectively, have been approved for the treatment of cancer patients (Modjtahedi and Essapen, 2009).

Patients should be tested for truncated Her2, as trastuzumab cannot bind to Her2-molecules lacking the extracellular domain [ 7].