Sentence examples for bind to exogenous targets from inspiring English sources

These findings expand the potential of the cystine-knot scaffold for future studies where multiple knottin loops can be simultaneously engineered to bind to exogenous targets.

Hence, the BL21 (DE3) luxS mutant, which was incapable of producing endogenous AI-2, but could bind to exogenous AI-2.

MOR binds to exogenous opioid drugs (e.g. morphine, heroin and methadone) with a high affinity.

No radioactivity was bound to exogenous DNA included in similar microsomal incubations, regardless of the type of microsomes used.

Donor CD4+ T cells are activated when their TCR binds to exogenous peptides presented in the context of class II MHC molecules on recipient APCs.

(E) Statistical analyses of the target number of ligands included in the MTLD: 795 ligand entries bind two targets; 551 ligand entries bind 3 5 targets; 189 ligand entries bind 6 10 targets; and 197 ligand entries bind to >10 targets; (F) Comparison of the conformation of a ligand bound to different targets.

This (indirect) diversity measure has its disadvantages as similar ligands can bind to different targets or alternatively, structurally diverse ligands may bind to the same target.

CaM and CaM-like proteins bind to their targets by anchoring hydrophobic residue of the target.

Drugs that bind to common targets likely exert similar activities.

Finally, PPI targets usually lack natural molecules that bind to the target PPI interface.

Conversely, cells expressing exogenous GPC6 or NFAT1 showed significantly reduced luciferase activity compared with the control cells, indicating GPC6 and NFAT1 inhibit the association of β-catenin with the TCF transcription factors to form transcriptionally active complexes that bind to Wnt target genes.