Sentence examples for bind to estrogen response from inspiring English sources
As transcription factors, active homodimers and heterodimers of ERα and ERβ bind to estrogen response elements (EREs) in nuclear and mitochondrial DNA, increasing the transcription of target genes [101].
However, because ERR can bind to estrogen response elements, a possible overlap between ER and ERR action may exist.
It has been demonstrated that pure antiestrogen ER complex can bind to estrogen response elements, but that the resultant transcriptional unit is inactive [ 52].
As mediated by estrogen, ERα can directly bind to estrogen response elements or indirectly interacts with chromatin through tethering to other transcription factors, such as coactivators or corepressors [ 13].
Activation of the target gene by 17β-estradiol activates both ERα and ERβ to increase transcriptional activities when dimers of the liganded receptors bind to estrogen response elements (ERE) which are specific DNA palindrome sequences located in the promoter region of estrogen-regulated target genes (Klinge 2001).
ERs act as ligand-activated transcription factors in the nucleus that specifically bind to estrogen response elements (EREs) in the promoters of target genes such as the human oxytocin, prolactin, cathepsin D, progesterone receptor, vascular endothelial growth factor, insulin-like growth factor (IGF -1, or c-fos genes [ 61], as dIGF -1matically shorn in Figure 3 (pathway 1).
The DNA-binding domain of ERα binds to estrogen response elements (EREs) in the regulatory region of estrogen-responsive genes, activating or repressing their transcription and consequently mediating physiological or tumorigenic effects.
The DNA-binding domain of ERα binds to estrogen response elements (EREs) in the promoter region of estrogen-responsive genes, activating or repressing their transcription and consequently mediating physiological or tumorigenic effects.
The dimeric receptor binds to estrogen response elements (EREs) in the promoters of estrogen-responsive genes.
Estrogen forms a complex with the estrogen receptor (ER) that binds to estrogen response elements (EREs) in the regulatory region of estrogen-responsive genes and regulates their transcription.
Estrogen forms a complex with the estrogen receptor (ER) that binds to estrogen response elements (EREs) in the promoter region of estrogen-responsive genes, regulates their transcription, and consequently mediates physiological or tumorigenic effects.
