Sentence examples for bind to estrogen from inspiring English sources
Estrogenic compounds should bind to estrogen receptors (ER).
BPA was shown to bind to estrogen receptors and to induce estrogenic activity, including stimulation of MCF-7 breast cancer-cell proliferation and induction of the expression of progesterone receptors.
The first two metabolites bind to estrogen receptors, primarily ERα receptors, and have estrogenic effects on bone, thermoregulatory centers in the central nervous system, and the vagina [ 17- 19].
Mimicking natural estrogens, they bind to estrogen receptor and modulate its activity.
Phytoestrogens can bind to estrogen receptors (Morito et al., 2001), which either mimics estrogen or works as antagonist (Fitzpatrick, 1999).
Here, we demonstrate presence of functional ERE at 2637/2655 base pair on Igf2/H19 DMR in testicular germ cells, which was found to bind to estrogen receptor β (ERβ) in the chromatin immunoprecipitation assay.
ERRα can bind to estrogen-response elements (ERE) containing the recognition motif AGGTCAnnnTGACCT; ERRα also recognizes the single consensus half-site sequence TNAAGGTCA, referred to as an ERR-response element (ERRE) [4].
The AR is able to bind to estrogen-responsive elements in ERα and prevent its growth-stimulatory effects, which is considered to be one of the mechanisms by which the AR is associated with a good prognosis in ER-positive breast cancer.
Although ERRs do not bind to estrogens, they share a significant and remarkable homology with ERs, particularly in DNA binding domain and LBD.
GPER exhibits many of the expected characteristics of an estrogen receptor, including the capability to bind to estrogens, phyto- and xenoestrogens and even the ER antagonists 4-hydroxytamoxifen (OHT) and fulvestrant (ICI 182 780) [ 10, 19, 27, 28].
However, functional studies have shown that neither molluscan ERs nor ERR bind to estrogens or other sex steroids [ 19, 20, 93, 94, 132– 134] and ER and ERR gene transcription was not affected by exogenous estrogens [ 94, 135].
