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Exact(20)
Thus, interference can be low if two compounds bind to different sites of the substrate binding site [ 31].
Epothilones and paclitaxel compete for the same binding pocket on β-tubulin; however, epothilones and the taxanes bind to different sites on β-tubulin.
Based on our results, which demonstrate that the CpG and non-CpG PS DNA have the same stoichiometry with TLR9 but with different binding affinity, it implies that the CpG and non CpG DNA might bind to different sites of TLR9.
More interestingly, docking simulations reveal that some of the oxazolxanthone derivatives bind to different sites in the enzyme.
As MacMillan explains, in organic synthesis, chemists work to create new molecules that have the capacity to bind to different sites in the body.
Here we present results that show that PS and PREGAS bind to different sites in the ATD of the GluA2 subunit, which when combined with previous results from our lab, now identifies two binding domains for each neurosteroid.
Similar(40)
Till date many anticancer toxins are discovered that binds to different sites of actin.
The newfound gene's product is a protein that binds to different sites along the DNA, signaling the cell to activate the nearby genes.
It also appeared that SB 247464 and G-CSF bound to different sites on the receptor, given that the small compound was unable to compete with G-CSF receptor natural ligand to initiate the dimerization.
As exemplified in Figure 29a, successive AFM images showed many association and dissociation events, in which bR trimers were bound to different sites at the border between the crystal and noncrystalline areas.
Hit compounds were evaluated and categorized according to their ability to bind to different binding sites in the ATP-binding pocket.
More suggestions(25)
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