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It works by combining high-resolution photography with specialized fluorescent molecules that bind to different proteins and glow in different colors.
The researchers confirmed the identity of these cells by staining the lab-grown tissues with fluorescent antibodies that recognize and bind to different proteins synthesised only by each cell type.
Aptamers are short strands of synthetically designed DNA or RNA oligonucleotides that can be self-assembled into unique 3-dimensional structures and can bind to different proteins, cells or even small molecules at a high level of specificity and affinity.
Computed RMSD values of most MTLs (1,270 entries, ≈73.3%) were <2.0 Å (Figure 2F), indicating that most of the MTLs could bind to different proteins by adopting a similar conformation.
Date hubs bind to different proteins at different times.
The individual WD40 repeats can simultaneously bind to different proteins, making Rack1 a candidate platform for integrating several signaling pathways.
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Cells produce many different MHC class I molecules that are able to bind to different protein fragments.
Previous analyses on protein families in yeast and Escherichia coli, have shown by analysing GO terms, that different paralogous relatives within a superfamily tend to bind to different protein partners [54].
An inherently promiscuous drug can bind to different protein pockets that have a range of features, making it difficult to establish a general description of a drug's possible binding sites.
A very good enrichment was also observed for tetracycline (Fig. 2b) and the results comprised different tetracycline derivatives bound to different proteins (tetracycline repressors, Tetx monooxygenases, multidrug binding protein, elongation factor Tu, ribosomal subunit and a tetracycline aptamer).
Plasma Aβ is well known to originate in different organs and it also is known that Aβ binds to different proteins and cells in the blood, thereby possibly accounting for why plasma Aβ levels do not correlate with Aβ measured in CSF or CNS plaque burden measured by PET amyloid plaque imaging.
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bind to neuronal proteins
bind to different sections
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