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Likewise, many B-ZIP TFs bind to composite elements containing multiple TF families.
This situation has also been described for the ETS family member PU.1 and IRF4 which co-operatively bind to composite elements found in the promoters and enhancers of b-lymphoid and myeloid genes (43– 43).
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IRF4 functionally cooperates with AP-1 transcription factor heterodimer BATF Jun in binding to composite elements in T cells.
GABPα initially was observed interacting with GABPβ (another ETS protein) to bind a composite element (Batchelor et al. 1998).
Third, the proximity of the MYB and AuxRE binding sites in one of them (IAA19) suggested that ARF7/MYB77 heterodimers may bind the composite elements in the promoter of certain auxin-responsive genes.
Exceptionally, dehydration-responsive element binding proteins (DREBs) that bind to drought-response elements (DRE) cis-elements were substantially down-regulated (five down-regulated and two up-regulated).
The exposed elements bind to similar exposed elements on other Fn modules, leading to a specific aggregation [11].
The cytosolic ligand-bound receptors thus enter the nucleus and bind to regulate elements.
The GmGT-2A, GmGT-2B or their truncated versions could not bind to other elements tested.
Proteins that bind to these elements remain to be isolated.
GT proteins specifically bind to GT elements, and the elements are highly degenerated.
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