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tasiRNA synthesis, however, first requires functional miRNAs, which bind to and trigger cleavage of a non-coding TAS precursor RNA.
These molecules include adenosine [37], [38], which bind to and trigger their receptors on lymphocytes, macrophages, and neutrophils, thereby diminishing anti-bacterial defenses.
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This study was undertaken to investigate the mechanism though which S. aureus binds to and triggers localised bone destruction.
Pre proteins bind to translocase and trigger cycles of ATP binding and hydrolysis so that pre protein substrates are transported at the expense of energy [ 55].
Over the past few years, our research has focused on the population level, well-characterized and co-ordinated dynamic signaling response of macrophages to invading pathogens based on the TLRs 3 and 4. Briefly, in TLR4 signaling, upon bacterial component lipopolysaccharide (LPS) recognition, MyD88 and TRAM molecules bind to TLR4 and trigger their respective pathways [ 1].
When Wolf writes that neurochemicals are "vehicles for very profound human truths," he responds, wide-eyed, "I thought neurochemicals were vehicles that bind to receptors and trigger signal transduction molecules".
This as evidence of the possibility that miRNA could bind to lincRNAs and trigger degradation.
Extracellular histones bind to receptors and trigger activation of multiple signaling pathways in a single or combined manner.
At low concentrations, netrin-1 preferentially binds to CD146, whereas at high concentrations, netrin-1 could bind to UNC5B and triggers signals that counteract CD146 downstream signals to inhibit the growth of blood vessels.
The activation of NF- κB transcription factor induces expression of TNF α, which then binds to TNFRs and triggers the extrinsic apoptotic pathway, resulting in caspase-8 activation and subsequent caspase-3 activation.
Tetracycline (Tc) or its derivative doxycycline (dox) binds to TetR and triggers a conformational change that prevents the protein from binding to tetO.
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