Sentence examples for bind to and sequester from inspiring English sources

It has been reported that IL-1F7 forms a complex with IL-18 binding protein, which might bind to and sequester IL-18R accessory protein, thus inhibiting the effects of IL-18 [ 14].

p27W76X retains most of the cyclin/Cdk binding domain of p27 (aminoacids 28 to 90), therefore it could bind to and sequester in the cytoplasm the canonical p27 partners: Cyclins E and D1, Cdk2 and Cdk4.

We have previously shown that simple N-acyl or N-alkyl polyamines bind to and sequester Gram-negative bacterial lipopolysaccharide, affording protection against lethality in animal models of endotoxicosis.

In certain contexts, guanine nucleotide dissociation inhibitors (GDIs) bind to and sequester GDP-bound Rho1, reinforcing the inactive Rho1 state.

CAG repeat mRNAs bind to and sequester diverse proteins.

These competitive sponges bind to and sequester miRNAs, preventing them from interacting with their natural targets.

FAS-AS1 binds to and sequesters the RNA binding protein RBM5, inhibiting, in turn, exon 6 skipping and reducing sFAS expression.

It results from expression of a toxic CUG repeat-containing mRNA that binds to and sequesters specific RNA-binding proteins including muscleblind, which is involved in splicing regulation.

The CsrC sRNA binds to and sequesters the mRNA binding protein CsrA via multiple GGA motifs in the loops of predicted stem-loop structures and thereby competes with mRNAs for CsrA binding.

Tipping et al., [39] recently showed that Krz directly binds to and sequesters an inactive form of ERK, thus preventing its activation by the upstream kinase, MEK.

Indeed, we and others have shown that it binds to and sequesters c-Cbl from EGFR through this same tyrosine residue, thereby enhancing EGFR expression levels on the cell surface [25], [26], [27], [28].