Sentence examples for bind to and neutralize from inspiring English sources
These strategies include using laboratory-made, monoclonal antibodies that can immediately bind to and neutralize specific viruses or bacteria in a person who has been infected, but also protect, for a time, anyone who is likely to be exposed to a particular pathogenic species.
A highly attractive feature of aptamers as antithrombotics is their ability to encode for complementary "controlling agents" which selectively bind to and neutralize their active counterparts via Watson-Crick base pairing or, in a less selective and clinically characterized manner, cationic polymers that can counteract the activity of an aptamer or free/protein-complexed nucleic acid.
In principle, polyvalent anti-HBs antibodies will bind to and neutralize circulating virions and prevent subsequent graft infection.
Class III antibodies bind to and neutralize soluble antigens, and their mechanism of action often involves blocking of the soluble ligand from binding to its receptor.
In contrast, Bim, a proapoptotic Bcl-2 family member that can bind to and neutralize Mcl-1, is targeted by ERK phosphorylation for proteasome-dependent degradation.
Current therapeutics for neovascular AMD are two closely related antibody drugs, ranibizumab (trade name Lucentis) and bevacizumab (trade name Avastin), both of which bind to and neutralize VEGF [ 2, 3].
The BH3 mimetic, ABT-737, is a promising compound that potently binds to and neutralizes the prosurvival proteins Bcl-2, Bcl-xL, and Bcl-w, but not Mcl-1 or A1 [ 22].
Bevacizumab is a recombinant humanized monoclonal antibody IgG1 which selectively binds to and neutralizes the biological activity of vascular endothelial growth factor (VEGF) and inhibits its interaction with receptors VEGFR 1 and VEGFR 2 [ 13].
Yet a further mechanism proposes the ability of certain antibodies to bind to oligomers and neutralize their synaptotoxic effects directly [ 46].
10.7554/eLife.07467.009 Figure 4. Lamprey VLRBs bind to hemagglutinin and neutralize infection.
Omalizumab is a chimeric mAb that specifically binds to and neutralizes IgE, thereby preventing its interaction with mast cells and the subsequent release of histamine and other inflammatory mediators [1].
