Sentence examples for bind to and block from inspiring English sources

However, the retention of bonding potential across the EPCR-binding surface of the CIDRα1 domains does suggest that it might be possible to raise IgG, which present a chemical surface that mimics features of EPCR, containing the ability to bind to and block the EPCR-binding surfaces of all CIDRα1s.

Both CCR5 and CXCR4 have generated significant interest as targets for drug development; agents that bind to and block those receptors could inhibit HIV entry into cells.

Drugs that bind to and block α1-adrenoceptors (known as α1-adrenoceptor antagonists) inhibit the ability of catecholamines to constrict the blood vessels.

We define here the structural requirements for small peptides to competitively bind to and block the s4A position to prevent this intermolecular linkage and polymerisation.

Patients who have GVHD that is refractive to these agents may be treated with a monoclonal antibody, which is designed to bind to and block specific targets involved in generating immune responses.

MicroRNAs are small molecules that bind to and block messages that act as protein blueprints from being translated into proteins.

Ipilimumab is a fully human IgG1 monoclonal antibody that Bind to and blocks the activity of CTLA-4.

Contributing to this de-repression is AbbA, an anti-repressor that binds to and blocks AbrB from binding to DNA.

Macugen binds to and blocks vascular endothelial growth factor, or VEGF, a protein in the body that spurs the formation of blood vessels.

Decoy receptor 3 (DcR3) is a novel member of the TNF receptor superfamily, which binds to and blocks the activities of the ligands FasL and LIGHT.

We designed a chimeric protein, GFP FRATtide, wherein GFP acts as a biomarker for fluorescence detection, and FRATtide binds to and blocks the active site of glycogen synthase kinase-3β (GSK-3β) – a protein kinase involved in Wnt signaling.