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A series of binding analyses of RIN revealed that RIN can bind to a wider variety of CArG boxes in vivo than the consensus sequence previously determined in vitro.
The new envelope has a number of interesting properties, including the ability to bind to a wider range of target cells than the wild original.
Some MHC molecules can bind to a wider variety of protein fragments than others, and the number of these molecules present on the cell surface can also vary between individuals.
Compared with antibodies, aptamers can bind to a wider range of targets, and they have the advantages of low molecular weight, high stability, easy and reproducible synthesis, easy functionalization, lack of immunogenicity, rapid tissue penetration, and low toxicity.
As ADARs may bind to a wider range of pre-miRNAs than they successfully edit, the influence of ADARs on miRNA function may also extend beyond the subset of miRNA, which are edited.
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They bind to a wide variety of small molecules and fatty acids and carry of them to different parts of the body.
The high AUC result for WDI is expected since it contains marketed and in-development small molecule drugs that bind to a wide variety of protein targets.
1,4-Dihydropyridines are regarded as privileged structures for drug design, i.e. they tend to bind to a wide variety of receptor sites.
Aptamers are specific nucleic acid sequences that can bind to a wide range of nucleic acid and non-nucleic acid targets with high affinity and specificity.
Some biosorbents are non-selective and bind to a wide range of heavy metals with no specific priority, whereas others are specific for certain types of metals depending on their chemical composition.
Type VI collagen is able to bind to a wide variety of ECM proteins, including type II collagen (Bidanset et al., 1992), type XIV collagen (Brown et al., 1994), matrilin-1 (Wiberg et al., 2001), and decorin (Bidanset et al., 1992), thereby forming a network that anchors the chondrocyte to the PCM in articular cartilage.
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