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Filopodia act as cellular tentacles to bind to a surface then retract and pull the cell toward the bound surface.
It could be also possible that these effects are secondary consequences of the NFAP action: NFAP may bind to a surface receptor which activates a signalling pathway that leads to apoptosis and defective polar growth.
Because sperm respond to progesterone within seconds, scientists reasoned that the hormone must bind to a surface protein and not one within the cells, which would take longer for the progesterone to reach.
Furthermore, it is not known whether factor XII first has to bind to a surface before it can interact with the surface-bound factor XIIa in a two-dimensional process to become activated ("bound-substrate model") or if surface-bound factor XIIa activates a fluid-delivered form of factor XII ("free-substrate model").
These toxic oligomers, also referred to as amyloid-derived diffusible ligands (ADDLs), bind to a surface receptor on neurons and change the structure of the synapse, thereby disrupting neuronal communication.
For example, constituents of Echinacea might bind to a surface membrane receptor that is coupled to PLC, such as chemokine [ 22], glutamate [ 23], or purinergic receptors [ 24].
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We find that certain cap chiralities, such as (8, 4), are more stably bound to a surface that resembles a Ni0.27Fe0.73 bimetallic catalyst, whereas other chiralities, such as (9, 4), are more stable on a pure Ni surface.
We wanted to investigate if full-length MASP2 in complex with MBL also is capable of activating prothrombin when bound to a surface.
This may be understood in the theoretical framework developed by Cozens-Roberts et al., showing how receptor/ligand molecular bonds compete with mechanical forces in a hydrodynamic shear field to maintain a particle specifically bound to a surface through molecular links.
Some advantages are the following: (1) The MassCode system employs primers, probes, targets and codes that are all in homogeneous solution during target hybridization steps rather than bound to a surface or interacting with a solid/liquid interface as with suspension arrays and microarrays [30] [33].
Likewise, it is not necessary that the DNA probes are physically bound to a surface.
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CEO of Professional Science Editing for Scientists @ prosciediting.com