Sentence examples for bind to a specific mRNA from inspiring English sources
ASO are chemically modified stretches of single stranded DNA designed to bind to a specific mRNA and selectively suppress its translation.
For instance, using short ncRNAs as input, the set of allosterically controlled nucleic acids can be activated when specific effector molecules are present and release short RNA strands that bind to a specific codon in mRNA thus blocking protein synthesis.
Briefly, when intracellular levels of tryptophan are high, tryptophan binds to TRAP, making the protein able to bind to a specific sequence in the mRNA leader sequence of the trp operon.
DNAzymes or catalytic oligonucleotides are new classes of gene targeting molecules that bind and cleave a specific mRNA, resulting in decreased protein expression.
The function of these activities for eIF4AIII within the EJC is not fully understood and eIF4AIII has been suggested to act as an 'RNA clamp' bound to a specific site on mRNA [11].
The model tracks all ribosomes and transfer RNA (tRNA) molecules in a cell each of which is either freely diffusing or bound to a specific messenger RNA (mRNA) molecule at a specific codon position at any time point (Extended Experimental Procedures).
It binds to a specific subset of mRNAs, associates with polysomes and localizes to RNA processing bodies (P bodies) and to stress granules.
It is a tantalizing idea that ribosomes bound to a specific set of mRNAs could be targeted to different subcellular compartments waiting for the right moment to start making specific proteins.
In a study of metastatic breast cancer, they determined that when the protein TARBP2 binds to a specific structural element in mRNA transcripts, it increases the likelihood that cancer cells will become invasive and spread.
That prediction was confirmed by molecular studies showing that Pum2 binds to a specific sequence in the 5'UTR of P2PR mRNA to modulate P2PR expression [ 3].
