Sentence examples for bind to a specific ligand from inspiring English sources
A general characteristic of the proteins that bind noncovalently to the cell wall is the presence of one or more so-called cell wall-binding domains (CWBDs) that bind to a specific ligand of the cell wall.
Aptamers are single-stranded DNA or RNA molecules that can selectively bind to a specific ligand with high affinity and specificity.
They are anchored to the membrane with one transmembrane domain, and have a large periplasmic sensing domain which is proposed to bind a specific ligand.
In contrast, using a competitive-binding assay will allow for identifying ligands that bind to a specific site on the target.
By changing the amino acid sequence of three targeting loops clustered at one end of the protein, an Adnectin can be designed to bind to a specific disease target, such as a receptor, ligand or protein with nanomolar or picomolar affinity, and potency and specificity comparable to or better than antibodies.
This has the advantage that additional constraints of arbitrary complexity can be easily added to a query, such as physicochemical properties of molecules, to consider affinity data from the ChEMBL database or even to exclude ligands that bind to a specific target.
However, the only ligand which was unequivocally demonstrated to bind to a specific V2R is a member of the ESP family, namely ESP1 (Kimoto et al. 2005, 2007).
Each lymphocyte bears receptors that bind to a specific antigen.
Screening approaches using peptide phage display libraries are effective for identifying peptides able to bind to specific ligand targets as well as identifying peptides with novel properties.
Only stabilized scTCR and MHC variants resisted thermal unfolding and still bound to a structurally specific ligand after the heat shock.
Because ankyrin repeats often serve as a protein interaction site (Li et al., 2006), we hypothesized that the ANKR2 domain of Varp also binds a specific ligand(s) and that the ANKR2 domain alone functions as a dominant negative construct that disrupts the endogenous ANKR2 ligand interaction in melanocytes.
