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The metal ions (usually Cu) bind to a specific domain in the protein called the octameric repeat region.
They bind to a specific domain of the prokaryotic 30 S ribosomal subunit and interfere with protein synthesis causing either inhibition of cell growth or cell death [ 1, 2].
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Rapamycin binds to a specific domain of mTOR and FKBP12 to form a sandwich-like structure that confers an unusually high specificity for rapamycin [61].
Numerous casts are present in the renal tubules, which are formed when light chains bind to a specific peptide domain on the Tamm-Horsfall protein [ 17]; variations in CDR3 in both the κ and λ light chains influence binding [ 20].
Since Wise had previously been shown to bind to a specific region in the extracellular domain of Lrp5/6, we aligned this region in Lrp5/6 with Lrp4 revealing a remarkable degree of conservation.
A general characteristic of the proteins that bind noncovalently to the cell wall is the presence of one or more so-called cell wall-binding domains (CWBDs) that bind to a specific ligand of the cell wall.
Each TM domain may bind to a specific set of lipids, thus generating a lipid shell of distinct composition around them.
The TNF-R1 ligation induces receptor trimerisation and the recruitment of the adaptor protein TNF-R1-associated death domain protein (TRADD) that binds to a specific death domain (DD) in the cytoplasmic domain of TNF-R1.
However, these components should be bound to a specific application domain in order to be effectively reused.
In addition to these proteins, E6 also binds to a specific group of PDZ-domain-containing proteins, including hScrib, hDlg, MAGI-family proteins, MUPP1, PATJ, and PTPN3.
PfEMP1 is thought to bind to A and B sugars and a specific variant from a rosetting parasite clone binds to the group A trisaccharide via the DBLα domain (Ref. 95).
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CEO of Professional Science Editing for Scientists @ prosciediting.com